To view Richard Fishel's PubMed listing click here.

 

The HsRAD51B-HsRAD51C stabilizes the HsRAD51 nucleoprotein filament

Amunugama R, Groden J, Fishel R.

DNA Repair. 2013 Jun 27. [Epub ahead of print]. doi: 10.1016/j.dnarep.2013.05.005 [PDF] [Supp. Data]

 

ATP-dependent nucleosome unwrapping catalyzed by human RAD51

North JA, Amunugama R, Klajner M, Bruns AN, Poirier MG, Fishel R.

Nucleic Acids Res. 2013 Jun 11. [Epub ahead of print]. doi: 10.1093/nar/gkt411 [PDF] [Supp. Data]

 

The mechanism of mismatch repair and the functional analysis of mismatch repair defects in Lynch syndrome

Martín-López JV, Fishel R.

Fam Cancer. 2013 Apr 10 [Epub ahead of print]. doi: 10.1007/s10689-013-9635-x [PDF]

 

Regulation of the nucleosome unwrapping rate controls DNA accessibility

North JA, Shimko JC, Javaid S, Mooney AM, Shoffner MA, Rose SD, Bundschuh R, Fishel R, Ottesen JJ, Poirier MG

Nucleic Acids Res. 2012 Nov 1;40(20):10215-27. doi: 10.1093/nar/gks747 [PDF] [Supp. Data]

 

Homologous recombination in eukaryotes

Amunugama R, Fishel R

Prog Mol Biol Transl Sci. 2012;110:155-206. doi: 10.1016/B978-0-12-387665-2.00007-9 [PDF?]

 

The hMSH2(M688R) Lynch syndrome mutation may function as a dominant negative

Martín-López JV, Barrios Y, Medina-Arana V, Andújar M, Lee S, Gu L, Li GM, Rüschoff J, Salido E, Fishel R

Carcinogenesis. 2012 Sep;33(9):1647-54. doi: 10.1093/carcin/bgs199 [PDF] [Supp. Data]

 

ATP alters the diffusion mechanics of MutS on mismatched DNA

Cho WK, Jeong C, Kim D, Chang M, Song KM, Hanne J, Ban C, Fishel R, Lee JB

Structure. 2012 Jul 3;20(7):1264-74. doi: 10.1016/j.str.2012.04.017 [PDF] [Supp. Data]

 

RAD51 protein ATP cap regulates nucleoprotein filament stability

Amunugama R, He Y, Willcox S, Forties RA, Shim KS, Bundschuh R, Luo Y, Griffith J, Fishel R

J Biol Chem. 2012 Mar 16;287(12):8724-36. doi: 10.1074/jbc.M111.239426 [PDF] [Supp. Data]

 

Human MSH2 (hMSH2) protein controls ATP processing by hMSH2-hMSH6

Heinen CD, Cyr JL, Cook C, Punja N, Sakato M, Forties RA, Lopez JM, Hingorani MM, Fishel R

J Biol Chem. 2011 Nov 18;286(46):40287-95. doi: 10.1074/jbc.M111.297523 [PDF] [Supp. Data]

 

Subunit interface residues F129 and H294 of human RAD51 are essential for recombinase function

Amunugama R, Fishel R

PLoS One. 2011;6(8):e23071. doi: 10.1371/journal.pone.0023071 [PDF]

 

Histone fold modifications control nucleosome unwrapping and disassembly

Simon M, North JA, Shimko JC, Forties RA, Ferdinand MB, Manohar M, Zhang M, Fishel R, Ottesen JJ, Poirier MG

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12711-6. doi: 10.1073/pnas.1106264108 [PDF] [Supp. Data]

 

A quantitative model of nucleosome dynamics

Forties RA, North JA, Javaid S, Tabbaa OP, Fishel R, Poirier MG, Bundschuh R

Nucleic Acids Res. 2011 Oct;39(19):8306-13. doi: 10.1093/nar/gkr422

 

Phosphorylation of histone H3(T118) alters nucleosome dynamics and remodeling

North JA, Javaid S, Ferdinand MB, Chatterjee N, Picking JW, Shoffner M, Nakkula RJ, Bartholomew B, Ottesen JJ, Fishel R, Poirier MG

Nucleic Acids Res. 2011 Aug;39(15):6465-74. doi: 10.1093/nar/gkr304

 

The base excision repair pathway is required for efficient lentivirus integration

Yoder KE, Espeseth A, Wang XH, Fang Q, Russo MT, Lloyd RS, Hazuda D, Sobol RW, Fishel R

PLoS One. 2011 Mar 23;6(3):e17862. doi: 10.1371/journal.pone.0017862

 

siRNA screening of a targeted library of DNA repair factors in HIV infection reveals a role for base excision repair in HIV integration

Espeseth AS, Fishel R, Hazuda D, Huang Q, Xu M, Yoder K, Zhou H

PLoS One. 2011 Mar 23;6(3):e17612. doi: 10.1371/journal.pone.0017612


Aspirin and low-dose nitric oxide-donating aspirin increase life span in a Lynch syndrome mouse model

McIlhatton MA, Tyler J, Kerepesi LA, Bocker-Edmonston T, Kucherlapati MH, Edelmann W, Kucherlapati R, Kopelovich L, Fishel R

Cancer Prev Res (Phila). 2011 May;4(5):684-93. doi: 10.1158/1940-6207.CAPR-10-0319

 

hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis

Pabla N, Ma Z, McIlhatton MA, Fishel R, Dong Z

J Biol Chem. 2011 Mar 25;286(12):10411-8. doi: 10.1074/jbc.M110.210989

 

MutS switches between two fundamentally distinct clamps during mismatch repair

Jeong C, Cho WK, Song KM, Cook C, Yoon TY, Ban C, Fishel R, Lee JB

Nat Struct Mol Biol. 2011 Mar;18(3):379-85. doi: 10.1038/nsmb.2009

 

XPB mediated retroviral cDNA degradation coincides with entry to the nucleus

Yoder KE, Roddick W, Hoellerbauer P, Fishel R

Virology. 2011 Feb 20;410(2):291-8. doi: 10.1016/j.virol.2010.11.016

 

Single-molecule analysis reveals the kinetics and physiological relevance of MutL-ssDNA binding

Park J, Jeon Y, In D, Fishel R, Ban C, Lee JB

PLoS One. 2010 Nov 12;5(11):e15496. doi: 10.1371/journal.pone.0015496

 

MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2)

Valeri N, Gasparini P, Braconi C, Paone A, Lovat F, Fabbri M, Sumani KM, Alder H, Amadori D, Patel T, Nuovo GJ, Fishel R, Croce CM

Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):21098-103. doi: 10.1073/pnas.1015541107

 

Modulation of mismatch repair and genomic stability by miR-155

Valeri N, Gasparini P, Fabbri M, Braconi C, Veronese A, Lovat F, Adair B, Vannini I, Fanini F, Bottoni A, Costinean S, Sandhu SK, Nuovo GJ, Alder H, Gafa R, Calore F, Ferracin M, Lanza G, Volinia S, Negrini M, McIlhatton MA, Amadori D, Fishel R, Croce CM

Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6982-7. doi: 10.1073/pnas.1002472107

 

Nucleosome remodeling by hMSH2-hMSH6

Javaid S, Manohar M, Punja N, Mooney A, Ottesen JJ, Poirier MG, Fishel R

Mol Cell. 2009 Dec 25;36(6):1086-94. doi: 10.1016/j.molcel.2009.12.010

 

RelA/p65 functions to maintain cellular senescence by regulating genomic stability and DNA repair

Wang J, Jacob NK, Ladner KJ, Beg A, Perko JD, Tanner SM, Liyanarachchi S, Fishel R, Guttridge DC

EMBO Rep. 2009 Nov;10(11):1272-8. doi: 10.1038/embor.2009.197

 

DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets

Li LS, Morales JC, Veigl M, Sedwick D, Greer S, Meyers M, Wagner M, Fishel R, Boothman DA

Br J Pharmacol. 2009 Oct;158(3):679-92. doi: 10.1111/j.1476-5381.2009.00423.x

 

Acetylation of histone H3 at the nucleosome dyad alters DNA-histone binding

Manohar M, Mooney AM, North JA, Nakkula RJ, Picking JW, Edon A, Fishel R, Poirier MG, Ottesen JJ

J Biol Chem. 2009 Aug 28;284(35):23312-21. doi: 10.1074/jbc.M109.003202

 

Evidence that hMLH3 functions primarily in meiosis and in hMSH2-hMSH3 mismatch repair

Charbonneau N, Amunugama R, Schmutte C, Yoder K, Fishel R

Cancer Biol Ther. 2009 Jul;8(14):1411-20

 

Enrichment and characterization of histones by two-dimensional hydroxyapatite/reversed-phase liquid chromatography-mass spectrometry

Su X, Jacob NK, Amunugama R, Hsu PH, Fishel R, Freitas MA

Anal Biochem. 2009 May 1;388(1):47-55. doi: 10.1016/j.ab.2009.01.033

 

Current and emerging trends in Lynch syndrome identification in women with endometrial cancer

Resnick KE, Hampel H, Fishel R, Cohn DE

Gynecol Oncol. 2009 Jul;114(1):128-34. doi: 10.1016/j.ygyno.2009.03.003

 

Sequence context effect for hMSH2-hMSH6 mismatch-dependent activation

Mazurek A, Johnson CN, Germann MW, Fishel R

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4177-82. doi: 10.1073/pnas.0808572106

 

Real-time quantitative PCR and fast QPCR have similar sensitivity and accuracy with HIV cDNA late reverse transcripts and 2-LTR circles

Yoder KE, Fishel R

J Virol Methods. 2008 Nov;153(2):253-6. doi: 10.1016/j.jviromet.2008.07.032

 

Harnessing mismatch repair to model sporadic cancers

Fishel R, Groden J

Nat Methods. 2008 Mar;5(3):225-6. doi: 10.1038/nmeth0308-225

 

Nitric oxide-donating aspirin derivatives suppress microsatellite instability in mismatch repair-deficient and hereditary nonpolyposis colorectal cancer cells

McIlhatton MA, Tyler J, Burkholder S, Ruschoff J, Rigas B, Kopelovich L, Fishel R

Cancer Res. 2007 Nov 15;67(22):10966-75. doi: 10.1158/0008-5472.CAN-07-2562

 

hMSH4-hMSH5 adenosine nucleotide processing and interactions with homologous recombination machinery

Snowden T, Shim KS, Schmutte C, Acharya S, Fishel R

J Biol Chem. 2008 Jan 4;283(1):145-54. doi:

 

DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics

Ikura T, Tashiro S, Kakino A, Shima H, Jacob N, Amunugama R, Yoder K, Izumi S, Kuraoka I, Tanaka K, Kimura H, Ikura M, Nishikubo S, Ito T, Muto A, Miyagawa K, Takeda S, Fishel R, Igarashi K, Kamiya K

Mol Cell Biol. 2007 Oct;27(20):7028-40. doi:

 

Liquid chromatography mass spectrometry profiling of histones

Su X, Jacob NK, Amunugama R, Lucas DM, Knapp AR, Ren C, Davis ME, Marcucci G, Parthun MR, Byrd JC, Fishel R, Freitas MA

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 May 1;850(1-2):440-54. doi: 10.1016/j.jchromb.2006.12.037

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